Intravenous clonidine use in a neonate experiencing opioid-induced myoclonus.

USE of clonidine in the management of pain and opioid taper is well-established for adults. Various treatment modalities have been described, ranging from abrupt opioid cessation with clonidine substitution to gradual taper with clonidine as an adjunct. Oral administration of clonidine in neonatal abstinence syndrome has been cited as safe and effective. Short-term use of intravenous clonidine for sedation in children has been recently reported in the literature. This report describes prolonged and continuous use of intravenous clonidine in the management of opioid-induced myoclonus and opioid taper in a neonate.